| Bioactivity | 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC50s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL[1][2][3]. |
| Invitro | 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows anti-Helicobacter pylori activity, with the MIC of 10 μg/mL, and has no effect on Helicobacter pylori urease activity at the concentration of 300 μg/mL[1].1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone (5-500 μM) shows a dose-dependent diacylglycerol acyltransferase (DGAT) inhibition, with an IC50 of 20.1 μM[3].1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone (5-20 μM) inhibits leukotriene biosynthesis in human polymorphonuclear granulocytes, with an IC50 of 10.1 μM[4]. |
| Name | 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone |
| CAS | 120693-53-0 |
| Formula | C23H31NO |
| Molar Mass | 337.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
CAS: 120693-53-0 F: C23H31NO W: 337.50
1-Methyl-2--4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II rece
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